This thesis examines techniques to automate configuration of an intrusion detection system utilizing hardware-assisted virtualization. These techniques are used to detect the version of a running guest operating system, automatically configure version-specific operating system information needed by the introspection library, and to locate and monitor important operating system data structures. This research simplifies introspection library configuration and is a step toward operating system independent introspection. An operating system detection algorithm and Windows virtual machine system service dispatch table monitor are implemented using the Xen hypervisor and a modified version of the XenAccess library. All detection and monitoring is implemented from the Xen management domain.