The presence of artificial intelligence has become so significant that it is imperative to examine how it will shape our future. With the aid of machines equipped with intelligence, the systems will be able to function without human intervention. Humans will play a secondary role in the complex future governed by intelligent machines. Over two sections, this book aims to examine this new ecosystem of complex systems powered by artificial intelligence. It covers a wide range of topics, including social and multi-agent technological systems, decision-making strategies, human-machine interaction and legislation, computational and biological intelligence, networks and deep learning, as well as other topics related to the impact of artificial intelligence on the science of complex systems.