The Golgi
| AUTHOR | Rothman, James; Warren, Graham; Rothman, James et al. |
| PUBLISHER | Cold Spring Harbor Laboratory Press (09/09/2011) |
| PRODUCT TYPE | Hardcover (Hardcover) |
Description
Identified more than 100 years ago by Camillo Golgi, the Golgi is a series of flattened cisternae that acts as a critical sorting and processing station for intracellular traffic. It receives cargo in vesicles exported from the endoplasmic reticulum and then dispatches this to the plasma membrane for secretion or directs it to other organelles, such as endosomes. The Golgi also plays an important role in carbohydrate metabolism: It is the major site for attachment of sugar moieties to proteins. Written and edited by experts in the field, thiscollection from Cold Spring Harbor Perspectives in Biology includes contributions that review the current models for Golgi traffic and detail the functions of the cargo carrying machinery, such as the COPI and COPII vesicles, the glycosidases and glycosyltransferases that determine the oligosaccharide composition of the cargo, the various sorting signals, GTPases, and adaptor proteins involved, and the tethers and SNAREs that mediate vesicle fusion and deliver the cargo to the next compartment on the pathway. The contributors also examine recent insights into Golgi architecture and positioning, and the way the Golgi fragments and regenerates during cell division. This volume, which includes discussions of Golgi bypass mechanisms, the evolution and diversity of the Golgi, and the involvement of Golgi in development and human inherited diseases, serves as a comprehensive reference for all cell biologists interested in this intriguing organelle.
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Product Format
Product Details
ISBN-13:
9780879698737
ISBN-10:
087969873X
Binding:
Hardback or Cased Book (Sewn)
Content Language:
English
More Product Details
Page Count:
322
Carton Quantity:
1
Product Dimensions:
7.20 x 0.90 x 10.20 inches
Weight:
2.00 pound(s)
Feature Codes:
Bibliography,
Index,
Dust Cover,
Table of Contents,
Illustrated
Country of Origin:
US
Subject Information
BISAC Categories
Science | Life Sciences - Biology
Science | Life Sciences - Microbiology
Science | Microbiology
Dewey Decimal:
571.656
Library of Congress Control Number:
2011023815
Descriptions, Reviews, Etc.
annotation
Identified more than a hundred years ago by Camillo Golgi, the Golgi is a series of flattened sacs that acts as a critical sorting and processing station for intracellular traffic. This volume covers recent insights into Golgi architecture, mechanisms of trafficking through the Golgi stacks, and more.
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publisher marketing
Identified more than 100 years ago by Camillo Golgi, the Golgi is a series of flattened cisternae that acts as a critical sorting and processing station for intracellular traffic. It receives cargo in vesicles exported from the endoplasmic reticulum and then dispatches this to the plasma membrane for secretion or directs it to other organelles, such as endosomes. The Golgi also plays an important role in carbohydrate metabolism: It is the major site for attachment of sugar moieties to proteins. Written and edited by experts in the field, thiscollection from Cold Spring Harbor Perspectives in Biology includes contributions that review the current models for Golgi traffic and detail the functions of the cargo carrying machinery, such as the COPI and COPII vesicles, the glycosidases and glycosyltransferases that determine the oligosaccharide composition of the cargo, the various sorting signals, GTPases, and adaptor proteins involved, and the tethers and SNAREs that mediate vesicle fusion and deliver the cargo to the next compartment on the pathway. The contributors also examine recent insights into Golgi architecture and positioning, and the way the Golgi fragments and regenerates during cell division. This volume, which includes discussions of Golgi bypass mechanisms, the evolution and diversity of the Golgi, and the involvement of Golgi in development and human inherited diseases, serves as a comprehensive reference for all cell biologists interested in this intriguing organelle.
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List Price $135.00
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