This third edition volume explores the latest advancements in genotoxicity testing and combines established assays with emerging technologies. Organized into five thematic sections, the book examines gene mutation assays, assays for chromosomal abnormalities, tests for primary DNA damage, assays in alternatives to animal models, as well as multipronged approaches to the assessment of genotoxicity. Written for the highly successful Methods in Molecular Biology series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips for troubleshooting and avoiding known pitfalls.

Authoritative and up-to-date, Genotoxicity Assessment: Methods and Protocols, Third Edition serves as a comprehensive resource for toxicologists, regulatory scientists, academicians, and students, dedicated to ensuring chemical safety in an evolving landscape of technological and scientific innovation.