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Protein Analysis Using Mass Spectrometry: Accelerating Protein Biotherapeutics from Lab to Patient

AUTHOR Lee, Mike S.; Lee, Mike S.; Ji, Qin C. et al.
PUBLISHER Wiley (06/19/2017)
PRODUCT TYPE Hardcover (Hardcover)

Description

Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development

  • Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery
  • Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs, instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis
  • Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives
  • Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
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Product Format
Product Details
ISBN-13: 9781118605196
ISBN-10: 1118605195
Binding: Hardback or Cased Book (Sewn)
Content Language: English
More Product Details
Page Count: 288
Carton Quantity: 12
Product Dimensions: 8.60 x 0.90 x 11.00 inches
Weight: 2.38 pound(s)
Feature Codes: Bibliography, Index
Country of Origin: US
Subject Information
BISAC Categories
Science | Spectroscopy & Spectrum Analysis
Science | Life Sciences - Biochemistry
Dewey Decimal: 572.6
Library of Congress Control Number: 2016058010
Descriptions, Reviews, Etc.
jacket back

Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development

Protein biotherapeutics has become a large portion of drug candidates and newly developed drugs aimed at conquering unmet medical needs. In recent years protein biotherapeutics have become an essential part of medical treatments for cancers and autoimmune diseases. Protein Analysis using Mass Spectrometry: Accelerating Protein Biotherapeutics from Lab to Patient describes the practical applications of mass spectrometry for protein analysis as well as their impact on accelerating drug discovery and development.

Analytical sciences used to develop technologies and methodologies to probe unknown systems quantitatively and qualitatively are one of essential components for delivering effective protein biotherapeutics. As protein molecules continue to be linked to diseases there is an increased opportunity for developing protein biotherapeutics to treat these diseases. The book brings together the most current advances in mass spectrometry technologies and related methods in order to accomplish this.

Doctors and nurses, lab managers, lab technicians, and pharmaceutical researches from academia and industry as well as researchers and developers will find this reference a useful tool in their research.

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publisher marketing

Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development

  • Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery
  • Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs, instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis
  • Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives
  • Brings together the most current advances in the mass spectrometry technology and related method in protein analysis
Show More

Editor: Lee, Mike S.
MIKE S. LEE, PHD is President of Milestone Development Services. He is actively involved with consulting, workshops, and symposia to connect industry needs with innovative technologies and solutions. His research interests include the applications of mass spectrometry for the analysis of proteins, natural products, drug metabolites, impurities, and degradants. Recent work has involved the development of automated orthogonal control systems for electrospray ionization. Formerly, Dr. Lee was director of analytical research and development at Bristol-Myers Squibb (BMS) Pharmaceutical Research Institute where he led interdisciplinary teams that contributed to the Food and Drug Administration's approval of Buspar(R) and Serzone, and the accelerated development and approval of TAXOL. Dr. Lee is a member of the American Society of Mass Spectrometry, American Association of Pharmaceutical Scientists, and the American Chemical Society. In addition, he has authored over forty scientific papers and issued patents.
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List Price $196.95
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Hardcover