Recent airpower operations revealed a deficiency in the United States Air Force's ability to precisely attack mobile targets at standoff ranges with minimal collateral damage. Future airpower operations will be executed in politically sensitive strategic environments and thus will require the ability to precisely destroy mobile targets that may have been strategically placed by an adversary in areas with a high risk of collateral damage. Current air-to-ground guided weapon systems, including man-in-the-loop guidance weapon systems, have limited collateral reduction capabilities and future autonomous precision standoff weapon systems may increase the risk and uncertainty associated with collateral damage due to technology limitations. The acquisition of a precision standoff man-in-the-loop weapon system through the modification of current weapon systems or the acquisition of a new weapon system may provide the United States Air Force a critically needed air-to-ground capability against mobile target in a high-risk collateral damage environment.