Paul McCarron is a down-on-his-luck gambling man with a debt he cannot see past. Melissa Kazas is a stripper, working the poles and the clients in an effort to provide her daughter with a better life. Steve Grace is a coke-addicted businessman who has recently found himself "unemployed". Chris Minen is a homeless man with no where to go and nothing to lose. They do not know one another but - for one night only - their fates are intertwined as they're invited to take part in The Run. The rules are simple: Armed with nothing but a flashlight each, they need to get from Point A through to Point B before the morning and, if they succeed, they win a life-changing amount of money but things aren't what they appear to be. And, when the sun is gone and the moon is full, the howls will echo through their very souls.