The Sanctified follows the migration of a soul from the past into the present and back again. It is primarily a love story, Caron's attachment to Veneta the catalyst that draws him to the New England town where she grows up under his watchful eye. Veneta, as an adult with children of her own, travels to Australia with her husband and it is there that Caron makes his first strong impact on her life. But it is back in the States that she becomes more aware of him during a frightening sance in a small house on a dark mountain road.