This document provides supplemental information to the President's 2014 Budget and serves as the Annual Report on the NNI called for in the 21st Century Nanotechnology Research and Development Act (P.L. 108-153, 15 USC 7501). The report also addresses the requirement for Department of Defense reporting on its nanotechnology investments, per 10 USC 2358 (see Appendix A). In particular, the report summarizes NNI programmatic activities for 2012 and 2013, as well as those currently planned for 2014 NNI budgets for 2012-2014 are presented by agency and PCA in Chapter 2 of this report. Information on the use of the Small Business Innovation Research (SBIR) and Small Business Technology Transfer Research (STTR) program funds to support nanotechnology research and commercialization activities, also called for in P.L. 108-153, is included at the end of Chapter 2. Activities that have been undertaken and progress that has been made toward achieving the four goals set out in the NNI Strategic Plan, activities in support of the NNI Nanotechnology Signature Initiatives (NSIs), changes in the balance of investments by PCA, and highlights from external reviews of the NNI and how their recommendations are being addressed, are presented in Chapters 3-6.