Drug formulation design is essential for developing a novel delivery system with desired specifications. The chapters on liposomes, nanocrystals, microneedles, and smart drug delivery systems will explain the need for these delivery systems. The optimization of the formulation plays a crucial role in achieving the desired characteristics for the dosage form, which will influence the presence of the desired drug concentration at the site of action and the establishment of therapeutic activity. Further, a chapter focusing on the dissolution mechanics and release kinetics offers a deeper understanding of the drug interaction at the molecular level. Comprehensively, referring to this book will provide insight into emerging technologies that are shaping the future of medicine.