In Taisho-era Japan, Tanjiro Kamado is a kindhearted boy who makes a living selling charcoal. But his peaceful life is shattered when a demon slaughters his entire family. His little sister Nezuko is the only survivor, but she has been transformed into a demon herself! Tanjiro sets out on a dangerous journey to find a way to return his sister to normal and destroy the demon who ruined his life.

After dealing with several demonic enemies aboard the Infinity Train, Tanjiro, Zenitsu and Inosuke must face the demon spirit of the train itself! Even if they can stop the demon train, the minions of Muzan Kibutsuji are still out there and Tanjiro must continue to improve his strength and skills. Learning the secret of the Hikonami Kagura and Flame Breathing will give him a powerful new advantage.