This handbook, "NASA Systems Engineering Handbook," is intended to provide general guidance and information on systems engineering that will be useful to the NASA community. It provides a generic description of Systems Engineering (SE) as it should be applied throughout NASA. A goal of the handbook is to increase awareness and consistency across the Agency and advance the practice of SE. This handbook provides perspectives relevant to NASA and data particular to NASA. This handbook describes systems engineering best practices that should be incorporated in the development and implementation of large and small NASA programs and projects. The engineering of NASA systems requires a systematic and disciplined set of processes that are applied recursively and iteratively for the design, development, operation, maintenance, and closeout of systems throughout the life cycle of the programs and projects. The scope of this handbook includes systems engineering functions regardless of whether they are performed by a manager or an engineer, in-house or by a contractor.