Engineering mathematics is a branch of applied mathematics where mathematical methods and techniques are implemented for solving problems related to the engineering and industry. It also represents a multidisciplinary approach where theoretical and practical aspects are deeply merged with the aim at obtaining optimized solutions. In line with that, the present Special Issue, 'Engineering Mathematics in Ship Design', is focused, in particular, with the use of this sort of engineering science in the design of ships and vessels. Articles are welcome when applied science or computation science in ship design represent the core of the discussion.