What development did anti-Semitism take in Spain when, after the Banishment Edict (1492), the country was no longer a locus of co-existence for different ethnic groups? This was the topic central to the colloquium in Konstanz (May 2000), the results of which are presented here. The colloquium united anthropologists, historians and literary scholars. This interdisciplinary approach focused on the factors, spaces, figures and voices involved in anti-Jewish (and hence anti-Semitic) discourse, both in their historical context and in their literary representation. On the latter issue, as much attention is given to the apologetic as to the critical aspect.