Liquid chromatography has become an indispensable tool for the preparative- and large-scale purifications of proteins and other fine chemicals. This book provides models which can be used to simulate various chromatographic operations and thus give good predictions for the transferation of laboratory methods into large-scale applications. Thus the book will be a useful tool for all Biotechnologists, Chemical Engineers, Biochemists, Microbiologists, and other Scientists working with separation techniques.