Apoptoz perifericheskikh limfotsitov pri revmatoidnom artrite
| AUTHOR | Marusenko Irina; Vezikova Natal'ya; Barysheva Ol'ga |
| PUBLISHER | Palmarium Academic Publishing (11/05/2014) |
| PRODUCT TYPE | Paperback (Paperback) |
Description
Apoptoz kak forma gibeli kletki yavlyaetsya obshchebiologicheskim mekhanizmom, otvetstvennym v granitsakh immunnoy sistemy za eliminatsiyu aktivirovannykh limfotsitov, vypolnivshikh svoyu funktsiyu, s tsel'yu preduprezhdeniya autoimmunnykh reaktsiy. Issledovano 172 bol'nykh revmatoidnym artritom i 25 zdorovykh donorov. Issledovalis' klinicheskie, laboratornye, instrumental'nye priznaki, otrazhayushchie aktivnost', stadiyu, variant zabolevaniya, takzhe issledovalis' kontsentratsii interleykina 2, interleykina 6, faktora nekroza opukholey, rastvorimogo Fas-liganda v syvorotke krovi. Otsenka aktivnosti apoptoza tsirkuliruyushchikh limfotsitov provodilas' metodom fluorestsentsii s ispol'zovaniem spetsificheskikh substratov po aktivnosti kaspazy 4 (aktivatora tsitokinov), kaspazy 8 (aktivatora effektornykh kaspaz) i kaspazy 6 (effektornoy kaspazy, osushchestvlyayushchey neposredstvenno destruktsiyu DNK i gibel' kletki) i opredeleniyu kolichestva 1- i 2-nitevykh razryvov DNK metodom fluorestsentsii DNK-tropnykh krasiteley - bromistogo etidiya, spetsifichnogo dlya vyyavleniya 2-nitevykh razryvov DNK, i 4', 6-diamidino-2-fenilindola, spetsifichnogo dlya vyyavleniya 1-nitevykh razryvov DNK."
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Product Format
Product Details
ISBN-13:
9783639809305
ISBN-10:
3639809300
Binding:
Paperback or Softback (Trade Paperback (Us))
Content Language:
Russian
More Product Details
Page Count:
108
Carton Quantity:
64
Product Dimensions:
6.00 x 0.26 x 9.00 inches
Weight:
0.37 pound(s)
Country of Origin:
US
Subject Information
BISAC Categories
Medical | General
Descriptions, Reviews, Etc.
publisher marketing
Apoptoz kak forma gibeli kletki yavlyaetsya obshchebiologicheskim mekhanizmom, otvetstvennym v granitsakh immunnoy sistemy za eliminatsiyu aktivirovannykh limfotsitov, vypolnivshikh svoyu funktsiyu, s tsel'yu preduprezhdeniya autoimmunnykh reaktsiy. Issledovano 172 bol'nykh revmatoidnym artritom i 25 zdorovykh donorov. Issledovalis' klinicheskie, laboratornye, instrumental'nye priznaki, otrazhayushchie aktivnost', stadiyu, variant zabolevaniya, takzhe issledovalis' kontsentratsii interleykina 2, interleykina 6, faktora nekroza opukholey, rastvorimogo Fas-liganda v syvorotke krovi. Otsenka aktivnosti apoptoza tsirkuliruyushchikh limfotsitov provodilas' metodom fluorestsentsii s ispol'zovaniem spetsificheskikh substratov po aktivnosti kaspazy 4 (aktivatora tsitokinov), kaspazy 8 (aktivatora effektornykh kaspaz) i kaspazy 6 (effektornoy kaspazy, osushchestvlyayushchey neposredstvenno destruktsiyu DNK i gibel' kletki) i opredeleniyu kolichestva 1- i 2-nitevykh razryvov DNK metodom fluorestsentsii DNK-tropnykh krasiteley - bromistogo etidiya, spetsifichnogo dlya vyyavleniya 2-nitevykh razryvov DNK, i 4', 6-diamidino-2-fenilindola, spetsifichnogo dlya vyyavleniya 1-nitevykh razryvov DNK."
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