Reduction of Simulation Time.- Recent Developments of TAU Adaptation Capability.- Adaptive Wall Function for the Prediction of Turbulent Flows.- Acceleration of CFD Processes for Transport Aircraft.- Efficient Combat Aircraft Simulations with the TAU RANS Code.- Improvement of Simulation Quality.- Universal Wall Functions for Aerodynamic Flows: Turbulence Model Consistent Design, Potential and Limitations.- Computational Modelling of Transonic Aerodynamic Flows Using Near-Wall, Reynolds Stress Transport Models.- Transition Prediction for Three-Dimensional Configurations.- Application of Transition Prediction.- Numerical Simulation Quality Assessment for Transport Aircraft.- Fluid Structure Coupling.- Computational Methods for Aero-Structural Analysis and Optimisation of Aircrafts Based on Reduced-Order Structural Models.- Development and Application of TAU-ANSYS Coupling Procedure.- Fluid-Structure Coupling: Simplified Structural Model on Complex Configurations.- Improvement of Shape Optimization Strategies.- Development of an Automated Artificial Neural Network for Numerical Optimization.- modeFRONTIER(c), a Framework for the Optimization of Military Aircraft Configurations.- One-Shot Methods for Aerodynamic Shape Optimization.- Automatic Differentiation of FLOWer and MUGRIDO.- Adjoint Methods for Coupled CFD-CSM Optimization.- Aerodynamic and Multidisciplinary Optimization of 3D-Configurations.- Aerodynamic Optimization for Cruise and High-Lift Configurations.- Aerodynamic Optimization of an UCAV Configuration.- Flexible Wing Optimisation Based on Shapes and Structures.- Multidisciplinary Optimization of an UAV Combining CFD and CSM.