The present study was design to determine antioxidant potential, nephroprotective and nephrocurative activity of some medicinal against cisplatin induced nephrotoxicity. You can find in this work cisplatin induced nephrotoxicity due to oxidative stress and phytochemical studies of medicinal plants have revealed that plants extracts consists of various amino acids, phenolic and Flavonoids content produced good antioxidants potential that are overcome the nephrotoxicity and produced nephroprotective and nephrocurative effect. You can use of this medicinal plants for next generation for treatment of various diseases like diabetes, hypertension, cardiactoxicity, heptotoxicity, tumour, and inflammation etc.