Pandemiya VICh-infektsii davno stala privychnoy real'nost'yu v sovremennom mire. Odnako poslednie poltora desyatiletiya prinesli yavnye uspekhi v eye sderzhivanii blagodarya primeneniyu antiretrovirusnoy khimioprofilaktiki i khimioterapii. V nastoyashchee vremya bolee 90% detey, rozhdyennykh VICh-infitsirovannymi materyami, ostayutsya nezarazhyennymi. Ezhegodno v mire rozhdaetsya bolee 2 mln. takikh detey. V Rossii ikh ne menee 30 tys. V vozraste polutora let oni snimayutsya s dispansernogo uchyeta. No intimnyy kontakt s virusom immunodefitsita cheloveka i toksicheskoe vozdeystvie antiretrovirusnykh khimiopreparatov na organizm beremennoy, na immunnuyu sistemu i gemopoez ploda i novorozhdennogo ne ostayutsya bez negativnykh posledstviy v forme dolgovremennoy subklinicheskoy immunopatologii. Kniga posvyashchena kliniko-laboratoromu issledovaniyu defitsita immunizabel'nosti u etikh detey v otnoshenii kalendarnoy vaktsinatsii protiv difterii, stolbnyaka i koklyusha, a takzhe vozmozhnosti eye korrektsii. Predstavlennye obzornye i original'nye materialy po immunologii, immunorekonstitutsionnoy farmakologii i vaktsinologii zainteresuyut immunologov, gematologov, vrachey-infektsionistov i pediatrov, zanyatykh vaktsinoprofilaktikoy infektsiy.