Molekulyarnoe Konstruirovanie I Sintez Gamk-Ergicheskikh Soedineniy
| AUTHOR | Oganesyan Eduard; Kodonidi Ivan |
| PUBLISHER | LAP Lambert Academic Publishing (02/27/2014) |
| PRODUCT TYPE | Paperback (Paperback) |
Description
Monografiya posvyashchena molekulyarnomu konstruirovaniyu i tselenapravlennomu sintezu novykh GAMK-ergicheskikh soedineniy. V dannoy monografii izlagayutsya vazhneyshie kriterii i kompleksnyy podkhod k konstruirovaniyu GAMK-ergicheskikh soedineniy, privodyatsya metody sinteza prognoziruemykh struktur. Osushchestvleno molekulyarnoe modelirovanie GAMK-ergicheskikh struktur na osnove logiko-strukturnogo podkhoda i komp'yuternykh tekhnologiy s posleduyushchim tselenapravlennym sintezom. Ispol'zovanie kompleksnogo podkhoda k konstruirovaniyu proizvodnykh pirimidin-4(1H)-ona pozvolilo minimizirovat' chislo sintezirovannykh soedineniy dlya polucheniya struktur s GAMK-ergicheskoy aktivnost'yu, yavlyayushchikhsya prakticheski netoksichnym veshchestvam. Na osnove izucheniya mekhanizma tsiklokondensatsii N-atsil- -ketoamidov avtory modifitsirovali usloviya sinteza, chto znachitel'no uvelichit' vykhod tselevykh produktov, zdes' zhe privodyatsya metodiki sinteza N-zameshchennykh proizvodnykh pirimidin-4(1H)-ona. Poluchennye dannye predstavlyayut interes dlya nauchnykh rabotnikov zanimayushchimsya poiskom biologicheski aktivnykh soedineniy i sozdaniem lekarstvennykh preparatov, khimikov sintetikov, farmakologov, studentov starshikh kursov, aspirantov meditsinskikh i farmatsevticheskikh VUZov."
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Product Format
Product Details
ISBN-13:
9783659518362
ISBN-10:
3659518360
Binding:
Paperback or Softback (Trade Paperback (Us))
Content Language:
Russian
More Product Details
Page Count:
112
Carton Quantity:
62
Product Dimensions:
6.00 x 0.27 x 9.00 inches
Weight:
0.39 pound(s)
Country of Origin:
US
Subject Information
BISAC Categories
Medical | Pharmacology
Descriptions, Reviews, Etc.
publisher marketing
Monografiya posvyashchena molekulyarnomu konstruirovaniyu i tselenapravlennomu sintezu novykh GAMK-ergicheskikh soedineniy. V dannoy monografii izlagayutsya vazhneyshie kriterii i kompleksnyy podkhod k konstruirovaniyu GAMK-ergicheskikh soedineniy, privodyatsya metody sinteza prognoziruemykh struktur. Osushchestvleno molekulyarnoe modelirovanie GAMK-ergicheskikh struktur na osnove logiko-strukturnogo podkhoda i komp'yuternykh tekhnologiy s posleduyushchim tselenapravlennym sintezom. Ispol'zovanie kompleksnogo podkhoda k konstruirovaniyu proizvodnykh pirimidin-4(1H)-ona pozvolilo minimizirovat' chislo sintezirovannykh soedineniy dlya polucheniya struktur s GAMK-ergicheskoy aktivnost'yu, yavlyayushchikhsya prakticheski netoksichnym veshchestvam. Na osnove izucheniya mekhanizma tsiklokondensatsii N-atsil- -ketoamidov avtory modifitsirovali usloviya sinteza, chto znachitel'no uvelichit' vykhod tselevykh produktov, zdes' zhe privodyatsya metodiki sinteza N-zameshchennykh proizvodnykh pirimidin-4(1H)-ona. Poluchennye dannye predstavlyayut interes dlya nauchnykh rabotnikov zanimayushchimsya poiskom biologicheski aktivnykh soedineniy i sozdaniem lekarstvennykh preparatov, khimikov sintetikov, farmakologov, studentov starshikh kursov, aspirantov meditsinskikh i farmatsevticheskikh VUZov."
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