In the monograph the latest Innovative direction on increase in energy efficiency of thermal and nuclear power plants of combined heat and power plant, state district power station, the NPP with use of the self-organizing Smart-MES "MES-T2 2020" System is given in real time. The Theory of Accidents and ideology of Self-organization of IT System which is capable to provide energy efficiency and fail-safety of power plants is described. The technology of creation of the Self-organizing Information Smart-MES System, and also an axiom of the Theory of Accidents, the logician of the prevention of Accidents, a paradigm of the Self-organizing IT System, structure, intellectuality and a multiagentnost of Smart-MES system is described. The book is addressed to students, scientists, experts power and IT industries, to the management of the Ministry of Energy and the Generation companies, everything who is interested in problems of economy of fuel. The no-cost technology of economy of fuel will allow the Generation companies to have additional many milliard profit.