The following reprint, Simulations and Applications of Augmented and Virtual Reality, brings together cutting-edge research exploring the transformative potential of AR, VR, and XR technologies. With the rapid adoption of these technologies across education, medicine, engineering, architecture, entertainment, art, and cultural heritage, this collection highlights their profound impact and the challenges associated with their implementation. Organized into three thematic areas-VR, AR, and XR simulations and applications, this reprint highlights groundbreaking advancements in immersive technologies and their diverse applications. Covering a wide spectrum of topics, it explores collaboration, content creation, human-computer interaction, and perception. This reprint emphasizes the practical applications of VR, AR, and XR technologies, including immersive training, virtual tourism, health and rehabilitation exergames, and industrial use cases. By presenting innovative solutions such as virtual reality classrooms, augmented reality tools for industrial operations, and extended reality telemedicine systems, this collection provides a thorough overview of the transformative potential of these technologies. It serves as a valuable resource for researchers, practitioners, and innovators seeking to drive impactful change across diverse fields.