The present investigations were made effect the effect of NPK application in different proportions on the growth and yield of two maize varieties (Zea Mays L.). The research was conducted on a sandy loam soil at the Agronomic Research Area, University of Agriculture, Faisalabad. Experiment was laid out in Randomized Complete Block Design (factorial) with a net plot size of 3X5m. Different levels of NPK were 0-0-0 (F0), 100-50-35 (F1), 175-80-60 (F2), and 250- 110-85 (F3) kg per ha. Two maize varieties, Golden (V1) and Sultan (V2) were used as source of trial. The crop was sown on well prepared seed bed keeping R X R distance 60 cm and P X P distance at 23 cm. The whole of the phosphorus and potash along with half of nitrogen fertilizers in form of DAP, Sulphate of potash and Urea respectively, were applied at sowing and the remaining amount of nitrogen fertilizer was applied at tasseling stage of the plant. All other cultural practices were kept normal and uniform in all the treatments. The data on desired parameters were collected by using standard procedures.