Innovation on Stomach Targetting Floating Tablets
| AUTHOR | Patel, Natvarlal M.; Mehta, Tarak Jayraj; Joshi, Amit K. |
| PUBLISHER | LAP Lambert Academic Publishing (04/12/2012) |
| PRODUCT TYPE | Paperback (Paperback) |
Description
Various approaches have been paused to increase the duration of oral dosage form in the stomach, including floating systems, swelling and expanding system, modified shape system, high density systems and other delayed gastric emptying devices. (Magnetic systems, Super porous -biodegradable hydrogel systems). Hydrodynamically balanced systems (HBS) -incorporated buoyant materials enable the device to float. Raft systems incorporate alginate gels - these have a carbonate component and, upon reaction with gastric acid, bubbles form in the gel, enabling floating. Swelling type of dosage form are such that after swelling, this product swell to extent that prevent their exit from the stomach through the pylorus. As, a result, the dosage form retained in the stomach for a longer period of time. These systems may be referred to as a "Plug type system," since they exhibit tendency to remain logged in the pyloric sphincters.
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Product Format
Product Details
ISBN-13:
9783848493456
ISBN-10:
3848493454
Binding:
Paperback or Softback (Trade Paperback (Us))
Content Language:
English
More Product Details
Page Count:
88
Carton Quantity:
90
Product Dimensions:
6.00 x 0.21 x 9.00 inches
Weight:
0.31 pound(s)
Country of Origin:
US
Subject Information
BISAC Categories
Medical | Pharmacology
Descriptions, Reviews, Etc.
publisher marketing
Various approaches have been paused to increase the duration of oral dosage form in the stomach, including floating systems, swelling and expanding system, modified shape system, high density systems and other delayed gastric emptying devices. (Magnetic systems, Super porous -biodegradable hydrogel systems). Hydrodynamically balanced systems (HBS) -incorporated buoyant materials enable the device to float. Raft systems incorporate alginate gels - these have a carbonate component and, upon reaction with gastric acid, bubbles form in the gel, enabling floating. Swelling type of dosage form are such that after swelling, this product swell to extent that prevent their exit from the stomach through the pylorus. As, a result, the dosage form retained in the stomach for a longer period of time. These systems may be referred to as a "Plug type system," since they exhibit tendency to remain logged in the pyloric sphincters.
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$62.84
