Experimental pharmacology is a study through experimental design in controlled situations which involves testing of pharmacologically unknown substance and pharmaceutical products in human and animal.It broadly covers the information about the history, source, physiochemical properties, physiological actions, mechanism of action, absorption, distribution, metabolism, excretion and therapeutic uses of drugs. Experimental pharmacology is one of the cornerstones of the drug discovery process. The Book focuses on the following core principles of pharmacology: pharmacokinetics; drug metabolism and transport; drug therapy in special populations; assessment of drug effects; drug discovery and development; pharmacogenomics and pharmacotherapy.