Ethics in Action: A Handbook for Institutional Animal Ethics Committees (IAEC) is a comprehensive guide designed to assist IAEC members, researchers, and administrators in ensuring ethical and regulatory compliance in animal research. The book provides a detailed understanding of IAEC roles, responsibilities, and operations, offering practical tools such as SOP templates, protocol review guidelines, and checklists for effective committee functioning. It covers national and international regulatory frameworks, with a special focus on CPCSEA guidelines, ensuring lawful practices in animal experimentation. Emphasizing the 3Rs principle-Replacement, Reduction, and Refinement-it promotes humane treatment of animals while maintaining scientific integrity. With case studies, real-life scenarios, and training resources, this handbook equips readers to navigate ethical challenges, improve animal welfare, and foster responsible research practices in academic and professional settings.