From the fruit of scientific research by scholars of special pedagogy and didactics and from research-action paths with territories comes this volume that addresses the theme of inclusion as a founding principle of professional action in different social and cultural contexts. Adopting an ecosystemic perspective, the text brings together theoretical contributions and avenues of inquiry, placing at the center of reflection highly topical issues concerning accessibility, personalized instructional design, the life project, and new methodologies of inclusive teaching with attention to the role of technologies and, among them, Artificial Intelligence.The volume is a valuable update for teachers, educators and professionals involved in building inclusive contexts and training trainers.