This report examines digitalisation's effects on science, technology and innovation and the associated consequences for policy. In varied and far-reaching ways, digital technologies are changing how scientists work, collaborate and publish. While examining these developments, this book also assesses the effects of digitalisation on longstanding policy themes, from access to publicly funded research data, to the diffusion of technology and its absorption by firms. New and emerging topics are also explored. These include the roles of artificial intelligence and blockchain in science and production, using digital technology to draw on the collective intelligence of the scientific community, advances in the digitalisation of biotechnology, and possible "dark sides" of digitalisation.