The main objective of the Cancer Incidence in Five Continents (CI5) series, published by the International Agency for Research on Cancer (IARC) and the International Association of Cancer Registries (IACR), is to present comparable data on cancer incidence for all countries around the world for which high-quality data have been made available by population-based cancer registries. CI5 is an invaluable source of information about the global burden and distribution of cancer, and Volume XI has a wider coverage than ever, presenting high-quality standardized data for cancers diagnosed during the period 2008-2012 from 343 cancer registries in 65 countries.