This thesis is the outcome of the research which I conducted in the

Department of Community Medicine in collaboration with department of Nephrology,

Institute of Medical Sciences, Banaras Hindu University. In this thesis, I have

endeavored to uncover the study of Low Acid Diet in pre-dialysis CKD patients with

reference to serum Bicarbonate level and dietary habits.

Despite numerous research, the query, about Role of Low Acid Diet in predialytic

CKD patients remains uncertain, and the CKD patients of this region have not

been studied for serum Bicarbonate values.

Another factor to be studied was based on the hypothesis that the low acid diet

could slow the decline of GFR, however this assertion has not been fully

substantiated, It is believed that it is complex and involves the interplay of multiple

factors, many of which are not elucidated.

This work is an attempt to study the pre-dialysis chronic kidney disease

patients and the effect of the role of low acid diet counseling on serum bicarbonate

level and GFR.

This thesis is categorized into seven parts. In the first part introduction to CKD

and nutrition related studies in pre-dialysis CKD patients and aims & objectives of the

thesis is mentioned. Second part describes the literature available on CKD Metabolic

Acid, Low Acid Diet and role of dietary intervention in CKD patients. Third part

elaborates the detailed material and methods employed in the present study. Fourth

part comprised of finding of the first objective the. Fifth part deals with the second

objectives and the Sixth, part deals with the effect of dietary intervention on predialysis

CKD patients Finally, in the last part the summary and conclusion of the

research work is given.