Toxic Ties follows Chanel, a fiercely loyal and creative African American woman in her mid-20s, as she battles betrayal, harassment, and deep personal wounds growing out of broken friendships, toxic relationships, and community drama in Chicago. Her story is one of survival and resilience-facing violence, courtroom battles, and emotional reckonings as she navigates friendships that turn to feuds and enemies lurking in familiar spaces.

After enduring the fallout of betrayal-friends and partners turning against her-Chanel finds empowerment by launching her "New Rules" blog and podcast. This platform becomes both an outlet and beacon for women tackling similar trauma and cultural struggles. Chanel's journey is marked by a series of escalating challenges: from violent showdowns and legal drama to the pressure of healing in public while enemies scheme and alliances shift.

Her circle includes complex friends and adversaries: Kimberly and Tabriya (sisters, with their own guilt and need for forgiveness), Jamiya (volatile but seeking redemption), Rachel (manipulative and vengeful), Ladia, Chelsey and Amira (steadfast and supportive), and recurring figures from her romantic past (Dominick and Mario). Chanel's relationships evolve as she learns to set boundaries, reject toxic ties, and reclaim her power-even as old wounds resurface and new threats appear.

Throughout, Chanel's daughters, her mother, and her growing sense of self push her forward. By the end, she discovers that forgiveness isn't always necessary; choosing herself, protecting her peace, and building a life of purpose-on her own terms-is the true victory.