Nondestructive evaluation (NDE) is one of several technologies applied at NASA Glenn Research Center to determine atypical deformities, cracks, and other anomalies experienced by structural components. NDE consists of applying high-quality imaging techniques (such as x-ray imaging and computed tomography (CT)) to discover hidden manufactured flaws in a structure. Efforts are in progress to integrate NDE with the finite element (FE) computational method to perform detailed structural analysis of a given component. This report presents the core outlines for an in-house technical procedure that incorporates this combined NDE-FE interrelation. An example is presented to demonstrate the applicability of this analytical procedure. FE analysis of a test specimen is performed, and the resulting von Mises stresses and the stress concentrations near the anomalies are observed, which indicates the fidelity of the procedure. Additional information elaborating on the steps needed to perform such an analysis is clearly presented in the form of mini step-by-step guidelines. Abdul-Aziz, Ali and Downey, James and Ghosn, Louis J. and Baaklini, George Y. Glenn Research Center NASA/TM-2004-212904, E-14327 WBS 22-728-30-06 NONDESTRUCTIVE TESTS; COMPUTER AIDED DESIGN; FINITE ELEMENT METHOD; STRUCTURAL ANALYSIS; X RAY IMAGERY; STRUCTURAL DESIGN; IMAGING TECHNIQUES; DEFORMATION; DEFECTS; CRACKS; ANOMALIES