Instant New York Times Bestseller! "Best-selling author James Patterson populates his murder-mystery novels with cold-blooded killers and smart detectives" (USA Today). In Holmes is Missing, PI Brendan Holmes has committed the perfect crime--he's made himself disappear. Success has come quickly to Holmes, Marple & Poe Investigations. The New York City agency led by three detectives--Brendan Holmes, "the brain," Margaret Marple, "the eyes," and Auguste Poe, the "muscle"--with famous names and mysterious pasts is one major case away from cementing its professional reputation. But as a series of child abductions tests the PIs' legendary skills, the cerebral Holmes's absence leaves a gaping hole in the agency roster. Only by closing ranks and solving the mystery within can they recover all that's been lost.