This book covers the latest progress on wide topics of biocides R&D: prioncides, biofilms, topical biocides, new biocides synthesis, mechanisms, structure-activity relationship, hospital and topical disinfection, biocides environmental effect, naturally occurring biocides, oxidizing biocides, aldehyde biocides, boron derivative biocides, traditional and non-classical biocides from most known researchers in the fields worldwide. The latest prion inactivation breakthrough discovery by Stanley B. Prusiner's group is also included. Historically, it was the interplay of chemistry and microbiology that helped to discover new biocides and new methods of disinfection. Tight integration of chemistry & microbiology for effective biocides discovery and development is the major theme of this book. This approach makes this book especially valuable for researchers and traditional practitioners alike in biocide field. Recent progress in both chemistry and life sciences has provided tremendous new opportunities to evaluate old and new biocides with new hopes.